Author
University of PennsylvaniaORCID 0000-0003-3704-6136Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
7 papers
Recent·Most cited
Makayla L. Reed, Kyra L. Feuer, Penn Medicine BioBank, Rachel L. Kember
The paper uses polygenic scores to associate psychiatric disorder risk with laboratory tests, identifying physiological biomarkers across different ancestries.
Laura Vilar‐Ribó, Mariela V. Jennings, Aisha Sallah…·Sandra Sanchez‐Roige
This study identifies sex-specific genetic loci and correlations for alcohol use behaviors and their comorbidities using genome-wide association studies.
Christal N. Davis, Sylvanus Toikumo, Alexander Samir Hatoum…·Penn Medicine BioBank
Yousef Khan, Christal N. Davis, Zeal Jinwala…·Rachel L. Kember
This paper combines transdiagnostic and disorder-level GWAS to enhance genetic risk profiles for psychiatric disorders in multi-ancestry samples, identifying novel SNPs and shared genetic variance.
D Das, Shreyash Sonthalia, G. Stein-O.’Brien…·Dimitrios Avramopoulos
The paper analyzes single-cell transcriptomics data of iPSC-derived neurons and astrocytes to assess their similarity to in vivo counterparts and their disease-related gene expression patterns.
Kyra L. Feuer, Xi Peng, Christian Yovo, Dimitrios Avramopoulos
This study knocks out the DPYSL2-B isoform in human iPSC-derived neurons, showing reduced dendrite length and transcriptomic changes linked to mTOR signaling and schizophrenia.
Marah H. Wahbeh, Kyra L. Feuer, Christian Yovo…·Dimitrios Avramopoulos
CRISPR Del/Rei is a pipeline for scarless genome editing of iPSCs, achieving high efficiency and rare off-target effects in ~2 months.