Author

D. A. Helmerich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:fluorescence / live-cell microscopy· 3 Approach:microscopy & imaging analysis· 3 Research Focus:cell type annotation· 2 Research Focus:imputation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:dimensionality reduction· 1 Organism:human· 1

Frequent Co-Authors

M. Sauer· 4 shared G. Beliu· 2 shared M. Meub· 2 shared S. Doose· 2 shared A. Chizhik· 1 shared A. Ghosh· 1 shared A. I. Chizhik· 1 shared A. Kuhlemann· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersBiophysics

M. Sauer

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Decoding the molecular interplay of endogenous CD20 and Rituximab with fast volumetric nanoscopy

M. Sauer, A. Ghosh, M. Meub, D. A. Helmerich, S. Doose, P. Eiring, K. M. Kortuem

The paper develops TDI-DNA-PAINT and LLS microscopy to study CD20-rituximab interactions in B cells, revealing oligomeric states and polarization effects.

bioRxiv · Oct 9, 2023 · PreprintBiophysics

Sub-10 nm fluorescence imaging

M. Sauer, D. A. Helmerich, G. Beliu, D. Taban, M. Meub, A. Kuhlemann, S. Doose, M. Streit

This study identifies challenges in achieving sub-10 nm resolution in fluorescence imaging and proposes a method combining time-resolved detection and photoswitching fingerprint analysis to overcome these challenges.

bioRxiv · Feb 8, 2022 · PreprintBiophysics

Isotropic Three-Dimensional Dual-Color Super-Resolution Microscopy with Metal-Induced Energy Transfer

J. C. Thiele, M. Jungblut, D. A. Helmerich, R. Tsukanov, A. Chizhik, A. I. Chizhik, M. Schnermann, M. Sauer, O. Nevskyi, J. Enderlein

The paper combines MIET imaging with dSTORM to achieve isotropic 3D super-resolution and dual-color imaging of sub-cellular structures.

bioRxiv · Dec 20, 2021Biophysics

Multiple-labeled antibodies behave like single emitters in photoswitching buffer

M. Sauer, D. A. Helmerich, G. Beliu

This study examines how the degree of labeling affects the blinking behavior of multiple-labeled antibodies in dSTORM imaging, finding that spatial resolution remains consistent regardless of labeling.

ACS Nano · Oct 27, 2020Peer-reviewedBiophysics