Conditional knockout of RAD51-related genes in Leishmania major reveals a critical role for homologous recombination during genome replication
J. D. Damasceno, J. Reis-Cunha, K. Crouch, C. Lapsley, L. Tosi, D. Bartholomeu, R. McCulloch
This study shows that RAD51 and RAD51-related proteins are critical for DNA replication in Leishmania major, with RAD51 specifically impairing DNA synthesis and origin initiation.
bioRxiv · Oct 10, 2019Microbiology