Author

J. D. Damasceno

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

C. Lapsley· 2 shared R. McCulloch· 2 shared C. A. Marques· 1 shared D. Bartholomeu· 1 shared D. Beraldi· 1 shared E. M. Briggs· 1 shared J. Reis-Cunha· 1 shared K. Crouch· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

C. Lapsley

Mutual co-authors in cluster

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2 papers

Recent·Most cited

RAD51-mediated R-loop formation acts to repair transcription-associated DNA breaks driving antigenic variation in Trypanosoma brucei

M. J. Girasol, M. Krasilnikova, C. A. Marques, J. D. Damasceno, C. Lapsley, L. Lemgruber, R. Burchmore, D. Beraldi, R. Carruthers, E. M. Briggs, R. McCulloch

This study shows RAD51 interacts with RNA-DNA hybrids and repairs DNA breaks at the transcribed VSG in T. brucei, linking RNA-DNA hybrids to antigenic variation.

bioRxiv · May 11, 2023Microbiology

Conditional knockout of RAD51-related genes in Leishmania major reveals a critical role for homologous recombination during genome replication

J. D. Damasceno, J. Reis-Cunha, K. Crouch, C. Lapsley, L. Tosi, D. Bartholomeu, R. McCulloch

This study shows that RAD51 and RAD51-related proteins are critical for DNA replication in Leishmania major, with RAD51 specifically impairing DNA synthesis and origin initiation.

bioRxiv · Oct 10, 2019Microbiology