Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots
A. Dashti, M. Shekhar, D. Ben Hail, G. Mashayekhi, P. Schwander, A. des Georges, J. Frank, A. Singharoy, A. Ourmazd
The paper introduces a method to analyze conformational changes in biomolecules using single-particle cryo-EM data, revealing functional pathways in RyR1 that differ from discrete structure analyses.
bioRxiv · Jan 14, 2019 · PreprintBiophysics