Author

D. C. Schriemer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 3 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:structural biology· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

D. A. Crowder· 2 shared A. R. M. Michael· 1 shared A. Rafiei· 1 shared A. Sali· 1 shared A. Syed· 1 shared B. C. Amaral· 1 shared D. J. Saltzberg· 1 shared F. Filandr· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

D. A. Crowder

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Author profile →

3 papers

Recent·Most cited

Cell fixation improves performance of in situ crosslinking mass spectrometry while preserving cellular ultrastructure

A. R. M. Michael, B. C. Amaral, K. L. Ball, K. H. Eiriksson, D. C. Schriemer

This study introduces a formaldehyde-based fixation method that improves in situ XL-MS performance while preserving cellular ultrastructure in human A549 cells.

bioRxiv · Mar 29, 2024 · PreprintBiochemistry

Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology

F. Filandr, V. Sarpe, S. Raval, D. A. Crowder, M. F. Khan, P. Douglas, S. Coales, R. Viner, A. Syed, J. A. Tainer, S. P. Lees-MIller, D. C. Schriemer

This paper develops an HX-MS2 workflow using DIA methods for automated HX data analysis, improving validation and throughput in proteomics.

Nature Communications · Mar 11, 2024Peer-reviewedBiochemistry

Doublecortin engages the microtubule lattice through a cooperative binding mode involving its C- terminal domain

A. Rafiei, L. Lee, D. A. Crowder, D. J. Saltzberg, A. Sali, G. Brouhard, D. C. Schriemer

This study reveals how doublecortin binds to microtubules through a cooperative mechanism involving its C-terminal domain and C-tails, with implications for neurological disorders.

bioRxiv · Feb 17, 2021Biochemistry