Polysaccharides from the fungus Inonotus obliquus activate macrophages into a tumoricidal phenotype via interaction with TLR2, TLR4 and Dectin-1a
C. W. Wold, P. Christopoulos, M. Arias, D. Dzovor, I. Oynebraaten, A. Corthay, K. T. Inngjerdingen
This study shows that acidic polysaccharides from Inonotus obliquus activate macrophages into a tumoricidal phenotype through interactions with TLR2, TLR4, and Dectin-1a.
bioRxiv · Nov 11, 2020 · PreprintImmunology