Dispatched conformational dynamics couples transmembrane Na+ flux to release of lipid-modified Hedgehog signal
Q. Wang, D. E. Asarnow, K. Ding, Y. Zhang, Y. Ma, Y. Cheng, P. A. Beachy
This paper investigates how Na+ flux through DISP1 enables release of lipid-modified Hedgehog signals by analyzing structural and functional changes in DISP1 variants.
bioRxiv · Sep 5, 2020Biophysics