Convergent evolution in SARS-CoV-2 Spike creates a variant soup that causes new COVID-19 waves.
D. Focosi, R. Quiroga, S. McConnell, M. C. Johnson, A. Casadevall
This paper identifies convergent evolution in SARS-CoV-2 Spike protein mutations across variants, leading to increased viral fitness and immune escape, and suggests rethinking antibody therapies.
bioRxiv · Dec 5, 2022 · PreprintMicrobiology