Safe and effective two-in-one replicon-and-VLP minispike vaccine for COVID-19
A. A. Hennrich, D. H. Banda, M. Oberhuber, A. Schopf, V. Pfaffinger, K. Wittwer, B. Sawatsky, C. Riedel, C. K. Pfaller, K.-K. Conzelmann
This paper develops a safe and effective vaccine platform using rhabdovirus replicons that present the SARS-CoV-2 RBD as VLPs, inducing strong neutralizing antibodies in mice.
bioRxiv · Oct 2, 2020 · PreprintMicrobiology