Author

D. H. Heiland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 4 Research Focus:cell type annotation· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Assay:scRNA-seq· 3 Assay:spatial transcriptomics· 3 Approach:statistical model· 3 Research Focus:cell-cell communication· 2

Frequent Co-Authors

C. Fung· 2 shared D. Delev· 2 shared F. Scherer· 2 shared J. Beck· 2 shared J. Goeldner· 2 shared J. Kuekelhaus· 2 shared K. Joseph· 2 shared L. Vollmer· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

C. Fung

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Programs, Origins, and Niches of Immunomodulatory Myeloid Cells in Gliomas

T. E. Miller, C. A. K. El Farran, C. P. Couturier, Z. Chen, J. P. D'Antonio, J. Verga, M. A. Villanueva, L. N. G. Castro, Y. E. Tong, T. Al-Saadi, A. N. Chiocca, D. S. Fischer, D. H. Heiland, J. L. Guerriero, K. Petrecca, , B. E. Bernstein

The paper identifies four immunomodulatory programs in glioma-associated myeloid cells using scRNA-seq and shows they are driven by microenvironmental cues and therapies, not cell type or mutation status.

bioRxiv · Oct 24, 2023 · PreprintCancer Biology

Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts

Y. A. Yabo, P. M. Moreno-Sanchez, Y. Pires-Afonso, T. Kaoma, B. Nosirov, A. Scafidi, L. Ermini, A. Lipsa, A. Oudin, D. Kyriakis, K. Grzyb, S. K. Poovathingal, A. Poli, A. Muller, R. Toth, , A. Golebiewska

This study characterizes the tumor microenvironment in glioblastoma patient-derived xenografts and patient tumors, revealing phenotypic heterogeneity in microglia and their functional adaptations.

bioRxiv · Mar 5, 2023Cancer Biology

Spatiotemporal heterogeneity of glioblastoma is dictated by microenvironmental interference

V. M. Ravi, P. Will, J. Kuekelhaus, N. Sun, K. Joseph, H. Salie, J. von Ehr, L. Vollmer, J. K. Benotmane, N. Neidert, M. Follo, F. Scherer, J. Goeldner, S. P. Behringer, P. Franco, , D. H. Heiland

This study identifies microenvironmental factors driving transcriptional heterogeneity in glioblastomas through spatial transcriptomics, metabolomics, and proteomics.

bioRxiv · Feb 16, 2021 · PreprintCancer Biology

Lineage and Spatial Mapping of Glioblastoma-associated Immunity

V. M. Ravi, N. Neidert, P. Will, K. Joseph, J. Kuekelhaus, L. Vollmer, J. Goeldner, S. Behringer, F. Scherer, M. Boerries, M. Follo, T. Weiss, D. Delev, J. Kernbach, P. Franco, , D. H. Heiland

This study maps immune cell states and interactions in glioblastoma, identifying IL-10-driven T cell exhaustion and myeloid-lymphoid interactions contributing to immunosuppression.

bioRxiv · Jun 1, 2020 · PreprintCancer Biology