Single-molecule tracking reveals dual front door/back door inhibition of Cel7A cellulase by its product cellobiose
D. Nong, Z. K. Haviland, N. Zexer, S. A. Pfaff, D. J. Cosgrove, M. Tien, C. T. Anderson, W. O. Hancock
This study uses single-molecule tracking to show that cellobiose inhibits Cel7A cellulase by binding to both the product release site and the substrate binding tunnel.
bioRxiv · Jul 13, 2023Plant Biology