C-low threshold mechanoreceptor activation becomes sufficient to trigger affective pain in spinal cord-injured mice in association with increased respiratory rates
D. J. Noble, R. Dongmo, S. Parvin, K. K. Martin, S. M. Garraway
This study shows that C-low threshold mechanoreceptors (C-LTMRs) become pain-sensing neurons after spinal cord injury, leading to affective pain and increased respiratory rates in mice.
Frontiers in Integrative Neuroscience · Dec 21, 2022Peer-reviewedPhysiology