Author

D. M. D. Siu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:imaging· 2 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

K. C. M. Lee· 3 shared K. K. Tsia· 3 shared B. M. F. Chung· 1 shared D. K. H. Ng· 1 shared E. Y. Lam· 1 shared J. C. M. Ho· 1 shared J. S. J. Wong· 1 shared M. C. F. Yeung· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersCell Biology

K. C. M. Lee

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Dispersion-free inertial focusing (DIF) for high-yield polydisperse micro-particles filtration and analysis

K. C. M. Lee, B. M. F. Chung, D. M. D. Siu, S. C. K. Ho, D. K. H. Ng, K. K. Tsia

The paper introduces DIF, a method to focus polydisperse micro-particles without size-dependent dispersion, achieving high efficiency and uniformity in microfluidic applications.

bioRxiv · Jan 20, 2024Cell Biology

Information-Distilled Generative Label-Free Morphological Profiling Encodes Cellular Heterogeneity

M. C. K. Lo, D. M. D. Siu, K. C. M. Lee, J. S. J. Wong, M. C. F. Yeung, M. K. Y. Hsin, J. C. M. Ho, K. K. Tsia

CytoMAD improves label-free morphological analysis of cell heterogeneity across batches by distilling morphological information and enabling drug response prediction without manual annotation.

bioRxiv · Nov 6, 2023Bioengineering

Morphological profiling by high-throughput single-cell biophysical fractometry

Z. Zhang, K. C. M. Lee, D. M. D. Siu, Q. T. K. Lai, E. Y. Lam, K. K. Tsia

This paper develops a high-throughput single-cell imaging technique to quantify fractal properties of cell morphology, enabling classification of lung-cancer subtypes and tracking of cell-cycle progression.

bioRxiv · May 24, 2022 · PreprintCell Biology