LL-37 fights SARS-CoV-2: The Vitamin D-Inducible Peptide LL-37 Inhibits Binding of SARS-CoV-2 Spike Protein to its Cellular Receptor Angiotensin Converting Enzyme 2 In Vitro
A. Roth, S. Luetke, D. Meinberger, G. Hermes, G. Sengle, M. Koch, T. Streichert, A. R. Klatt
This study shows LL-37, a vitamin D-induced peptide, binds to SARS-CoV-2 spike protein and inhibits its interaction with ACE2, potentially preventing viral entry.
bioRxiv · Dec 2, 2020 · PreprintImmunology