Tumor-infiltrating nerves create an electro-physiologically active microenvironment and contribute to treatment resistance
A. Kovacs, D. W. Vermeer, M. Madeo, H. Reavis, S. J. Vermeer, C. S. Williamson, A. Rickel, J. Stamp, C. T. Lucido, J. Cain, M. Bell, M. Morgan, J.-Y. Yoon, M. A. Mitchell, N. Tulina, , P. D. Vermeer
The paper shows that tumor-infiltrating nerves contribute to treatment resistance and that chemotherapy increases tumor innervation.
bioRxiv · Apr 24, 2020Cancer Biology