M. Bell

Inhibition of NFAT promotes loss of tissue resident uterine natural killer cells and attendant pregnancy complications in humans

The paper identifies NFAT inhibition as a cause of reduced uterine natural killer (uNK) cells and pregnancy complications in humans through analysis of uterus transplant recipients.

Sequential Transcriptional Programs of Tissue Residency Drive Human Uterine NK Cell Development

This study identifies sequential transcriptional programs of tissue residency driving human uterine NK cell development through single-cell analyses.

Phenology across scales: an intercontinental analysis of leaf-out dates in temperate deciduous tree communities

The paper analyzes leaf-out variability across temperate deciduous forests in North America and Europe, finding similar intra-community variability despite differences in species richness and environmental conditions.

Novel in-silico predicted matrikines are differential mediators of in vitro and in vivo cellular metabolism

The paper presents an in silico to in vivo pipeline to identify novel matrikines that differentially influence cellular metabolism in vitro and in vivo.

Mechanical principles governing the shapes of dendritic spines

This study uses a biophysical model to explore mechanical principles governing dendritic spine shapes and their stability through actin structures and force regimes.

Cell shape regulates subcellular organelle location to control short-term Ca2+ signal dynamics in vascular smooth muscle cells

The paper shows how cell shape changes affect subcellular organelle positioning, altering Ca2+ signaling and phenotypic function in vascular smooth muscle cells.

Tumor-infiltrating nerves create an electro-physiologically active microenvironment and contribute to treatment resistance

The paper shows that tumor-infiltrating nerves contribute to treatment resistance and that chemotherapy increases tumor innervation.

Genetically Encoded, Multivalent Liquid Glycan Array (LiGA)

The paper introduces LiGA, a platform for analyzing glycan-lectin interactions using DNA barcoded phage displaying glycans, enabling in vitro and in vivo binding studies.

ImmunoPET as Stoichiometric Sensor for Glypican-3 in Models of Hepatocellular Carcinoma

This paper demonstrates that the immunoPET agent [89Zr]Zr-DFO-TAB-H14 specifically and stoichiometrically binds to GPC3 in human liver cancer models, serving as a potential in vivo sensor for HCC diagnosis and therapy selection.

Gq-mediated calcium dynamics and membrane tension modulate neurite plasticity

This study shows that Gq-mediated calcium dynamics and membrane tension regulate neurite retraction and synaptic disruption in PC12 cells and C. elegans.

Ecological and dietary differences between Ugandan chimpanzee communities with possible implications on tool use

This study compares ecological and dietary differences between Ugandan chimpanzee communities to explore their implications on tool use, finding that Sonso chimpanzees have higher food diversity but lower stick and insect nest availability, potentially explaining their limited tool use.

A new class of disordered elements controls DNA replication through initiator self-assembly

This study identifies a new class of disordered elements that drive liquid-liquid phase separation in DNA replication initiators in D. melanogaster.