Choroid-resident macrophages maintain local vasculature and RPE integrity and spontaneously regenerate following depletion
X. Yang, L. Zhao, M. M. Campos, M. Abu-Asab, D. Ortolan, N. Hotaling, K. Bharti, W. T. Wong
This study shows that choroidal macrophages maintain choroidal vasculature and RPE integrity, and their depletion leads to atrophy and structural changes, which can be reversed by regeneration.
bioRxiv · Dec 10, 2019 · PreprintImmunology