Multiple sites on glycoprotein H (gH) functionally interact with the gB fusion protein to promote fusion during herpes simplex virus (HSV) entry
Q. Fan, D. P. Hippler, Y. Yang, R. Longnecker, S. A. Connolly
This study identifies two gH mutations (H789Y and S830N) that partially restore HSV-1 entry function when paired with specific gB variants, suggesting functional interaction sites between gH/gL and gB.
mBio · Feb 28, 2023Peer-reviewedMicrobiology