Molecular Basis For The Specific And Multivariate Recognitions Of RNA Substrates By Human hnRNPA2/B1
B. Wu, S. Su, D. P. Patil, H. Liu, J. Gan, S. R. Jaffrey, J. Ma
This study determines the crystal structures of hnRNPA2/B1's RRM domains bound to RNA substrates, revealing sequence-specific recognition and suggesting a matchmaker mechanism, but not m6A binding.
bioRxiv · Jun 1, 2017Biochemistry