Immunoregulatory effect of metformin in monocytes exposed to SARS-CoV-2 spike protein subunit 1
Rafael Moura Maurmann, Kierstin L. Davis, Negin Mosalmanzadeh, Brenda Landvoigt Schmitt, D. Pence
This study investigates how metformin modulates monocyte inflammation in response to SARS-CoV-2 spike protein subunit 1, finding that AMPK activation is central to its anti-inflammatory effects.
Immunometabolism · Jan 1, 2026Peer-reviewedImmunology