Expanding the Substrate Scope of N- and O-Methyltransferases from Plants for Chemoselective Alkylation
E. Jockmann, F. Subrizi, M. K. F. Mohr, E. M. Carter, P. M. Hebecker, D. Popadic, H. C. Hailes, J. N. Andexer
This study expands the substrate scope of plant methyltransferases for chemoselective alkylation by testing aminophenols as methyl acceptors, achieving up to 62% yield in biocatalytic reactions.
bioRxiv · Jul 21, 2023Biochemistry