A screen of FDA-approved drugs identifies inhibitors of Protein Tyrosine Phosphatase 4A3 (PTP4A3 or PRL-3)
D. R. Rivas, M. V. C. Dela Cerna, C. N. Smith, B. G. Patty, D. Lee, J. S. Blackburn
The paper screens FDA-approved drugs to identify inhibitors of PTP4A3 (PRL-3), finding five specific inhibitors and two broad inhibitors that block PRL-3-induced migration without affecting cell viability.
bioRxiv · May 24, 2020Cancer Biology