Distinct features of multivesicular body-lysosome fusion revealed by a new cell-free content-mixing assay
M. A. Karim, D. R. Samyn, S. Mattie, C. L. Brett
The paper develops a cell-free assay to study MVB-lysosome fusion in yeast, identifying Pep12 as a key SNARE protein distinguishing this process from homotypic lysosome fusion.
bioRxiv · Oct 27, 2017Cell Biology