Mechanistic basis of teichoic acid transport by a gatekeeper flippase
Gonzalo Cebrero, Amrutha H. Chidananda, Eric Cester, Julien Dénéréaz, Elif Sena Demir, Alen T. Mathew, D. Ryan Bhowmik, Mario de Capitani, Jean-Louis Reymond, Natarajan Kannan, Fikri Y. Avci, Jan‐Willem Veening, Ahmad Reza Mehdipour, Camilo Pérez
The paper determines the mechanism of teichoic acid transport by the flippase TacF in Streptococcus pneumoniae using cryo-EM and computational methods.
Nature Communications · May 25, 2026Peer-reviewedBiochemistry