Identification and Characterization of Fbxl22, a novel skeletal muscle atrophy-promoting E3 ubiquitin ligase
D. C. Hughes, L. M. Baehr, J. R. Driscoll, S. A. Lynch, D. S. Waddell, S. C. Bodine
This study identifies Fbxl22 and its splice variant as E3 ubiquitin ligases involved in neurogenic muscle atrophy, showing their role in muscle atrophy and potential therapeutic relevance.
bioRxiv · Apr 24, 2020Physiology