Liquid-liquid phase separation and aggregation of a globular folded protein SUMO1
S. Arora, D. Saha Roy, S. Maiti, S. R. K. Ainavarapu
This study shows that the globular protein SUMO1 undergoes liquid-liquid phase separation and transitions to solid aggregates under crowded conditions, challenging the assumption that only intrinsically disordered proteins can undergo LLPS.
bioRxiv · Jun 10, 2023Biophysics