A distinct pool of Nav1.5 channels at the lateral membrane of murine ventricular cardiomyocytes
J.-S. Rougier, M. C. Essers, L. Gillet, S. Guichard, S. Sonntag, D. Shmerling, H. Abriel
This study investigates the role of 1-syntrophin in regulating sodium current at the lateral membrane of cardiomyocytes and identifies a sub-pool of Nav1.5 channels independent of 1-syntrophin and the PDZ-binding motif.
bioRxiv · Mar 9, 2019Physiology