Peripheral death by neglect and limited clonal deletion during physiologic B lymphocyte development
M. J. Willett, C. McNees, S. Sharma, A. M. Newen, D. Pfannenstiel, T. Moyer, D. Stephany, I. Douagi, Q. Wang, C. T. Mayer
The paper quantifies apoptosis and clonal deletion during B lymphocyte development, finding that most peripheral B cell death results from failed selection rather than clonal deletion.
bioRxiv · May 30, 2023 · PreprintImmunology