Pcbp1 constrains Oct4 expression in the context of pluripotency
Evgeny I. Bakhmet, Anna S. Zinovyeva, Andrey A. Kuzmin, D. V. Smirnova, Mikhail N. Gordeev, Eugeniy Petrenko, Nicolay D. Aksenov, Alexey N. Tomilin
This study shows Pcbp1 regulates Oct4 expression during differentiation, with loss of Pcbp1 causing premature differentiation and increased PrE specification.
bioRxiv · Sep 7, 2024 · PreprintCell Biology