Pcbp1 orchestrates amino acid metabolism burst during the naive-to-primed pluripotency transition
Evgeny I. Bakhmet, Evgenii V. Potapenko, Oleg Y. Shuvalov, Arseniy A. Lobov, Репкин Егор Алексеевич, Daria V. Kriger, Nadezhda E. Vorobyeva, Alexey N. Korablev, Anna S. Zinovyeva, Andrey A. Kuzmin, Nikolay Aksenov, Arthur Tigranovich Kopylov, Guangming Wu, Hans Robert Schöler, Alexey N. Tomilin
This study identifies Pcbp1's role in enhancing amino acid metabolism during the naive-to-primed pluripotency transition, linking its deficiency to embryo growth arrest and reduced protein synthesis.
Stem Cell Reports · Jun 4, 2026Peer-reviewedDevelopmental Biology