An rRNA fragment in extracellular vesicles secreted by human airway epithelial cells increases the fluoroquinolone sensitivity of P. aeruginosa
K. Koeppen, T. Hampton, S. Gerber, Y. A. Goo, B.-K. Cho, D. Vermilyea, D. Hogan, B. Stanton
This study identifies an rRNA fragment from human airway epithelial cell extracellular vesicles that enhances P. aeruginosa sensitivity to ciprofloxacin by downregulating the MexHI-OpmD efflux pump.
bioRxiv · Apr 19, 2022Microbiology