PNAG exopolysaccharide eradication gives neutrophils access to Staphylococcus aureus biofilm infections
R. M. Kratofil, T. E. Randall, J. W. Hommes, R. Sejuty, J. Chisholm, D. Raju, M. Vargas, P. L. Howell, G. B. Pier, D. W. Morck, J. J. Harrison, P. Kubes
This study shows that disrupting the PNAG biofilm matrix with PgaB allows neutrophils to access and clear S. aureus biofilms in vivo.
bioRxiv · Jan 23, 2023 · PreprintImmunology