The human developing cerebral cortex is characterized by an increased de novo expression of lncRNAs in excitatory neurons
D. A. Morales-Vicente, A. C. Tahira, D. Woellner-Santos, M. S. Amaral, M. G. Berzoti-Coelho, S. Verjovski-Almeida
The paper identifies evolutionary shifts in lncRNA expression in the developing human cerebral cortex, showing increased de novo expression in excitatory neurons and associations with autism spectrum disorder.
bioRxiv · Oct 26, 2023Evolutionary Biology