γ-Amino Carboxylic Acid Modification Enhances the Efficacy of PNAs Targeting miR-221-3p in A549 Cells
Youngsim Yoon, Na‐Rae Joo, Junghyun Min, Daeyoon Bae, Seohee Lee, Youngjun Choi
This study modifies PNAs targeting miR-221-3p with gamma-amino carboxylic acid to enhance their efficacy in A549 cells, showing improved binding and gene regulation.
bioRxiv · Jun 15, 2025 · PreprintMolecular Biology