CD40 agonistic-monovalent streptavidin fusion antibody for targeted neoantigen peptide delivery and potent cancer vaccination
Dahee Jung, Xiaoying Cai, Ziye Wan, Elie Abi Khalil, Nawon Lee, Neal Thomas Ramseier, Qing Bao, Zongmin Zhao, Ying Chuan Hu, Seung‐Oe Lim, Seung Young Lee
This paper develops a CD40 agonistic-monovalent streptavidin fusion antibody that delivers neoantigen peptides to APCs, enhancing cancer vaccine efficacy and tumor regression in mice.
Journal of Controlled Release · May 25, 2026Peer-reviewedImmunology