Sharks and rays have the oldest vertebrate sex chromosome with unique sex determination mechanisms
Taiki Niwa, Yoshinobu Uno, Yuta Ohishi, Mitsutaka Kadota, Naotaka Aburatani, Itsuki Kiyatake, Daiki Katooka, Michikazu Yorozu, Nobutaka Tsuzuki, Atsushi Toyoda, Wataru Takagi, Masaru Nakamura, Shigehiro Kuraku
This study identifies the oldest vertebrate sex chromosomes in sharks and rays, revealing a unique dosage-dependent sex determination mechanism distinct from other vertebrates.
Proceedings of the National Academy of Sciences · Jul 22, 2025Peer-reviewedEvolutionary Biology