Author

Wataru Takagi

Atmosphere and Ocean Research Institute, The University of TokyoORCID 0000-0002-7882-0223Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 3 Developmental Biology· 1 Genomics· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Approach:statistical model· 3 Organism:chicken / avian· 2 Assay:metabolomics· 2 Assay:whole-genome sequencing· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

Fumiya FurukawaiD· 2 shared Marino ShimizuiD· 2 shared Mitsutaka KadotaiD· 2 shared Shigehiro KurakuiD· 2 shared Susumu HyodoiD· 2 shared Taiki NiwaiD· 2 shared Akane KawaguchiiD· 1 shared Anna Yasunaga· 1 shared

Activity by Year

2024-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersDevelopmental Biology

Fumiya FurukawaORCID

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7 papers

Recent·Most cited

Tracing genome size dynamics in sharks and rays with inclusive sequence analysis by the Squalomix Consortium

Shigehiro Kuraku, Yawako W. Kawaguchi, Taiki Niwa, Ryo Misawa, Yohey Ogawa, Mitsutaka Kadota, Kazuhiro Saito, Waichiro Godo, Tatsuya Sakamoto, Wataru Takagi, Sachiko Isobe, Kenta Shirasawa, Akane Kawaguchi

The paper presents whole genome sequences of two elasmobranchs, analyzing genome size dynamics and genomic architecture, revealing correlations between chromosome size, repetitive elements, and gene duplication patterns.

Genome Research · Aug 1, 2026Peer-reviewedGenomics

Evolutionary insights into glucose production in vertebrate development: new findings from Arctic lamprey (Lethenteron camtschaticum)

Marino Shimizu, Wataru Takagi, Fumiya Furukawa

The paper investigates gluconeogenesis in Arctic lamprey development, finding increased glucose levels and distinct gene expression patterns compared to other vertebrates.

bioRxiv · May 26, 2026 · PreprintDevelopmental Biology

Transcriptional Activation of Estrogen Receptor-alpha and Estrogen Receptor-beta from Elephant Shark (Callorhynchus milii)

Ya Ao, Haruka Narita, Wataru Takagi, Susumu Hyodo, Michael E. Baker, Yoshinao Katsu

The paper studies estrogen receptor activation in elephant shark, finding three active ER genes and one unresponsive gene, with similar estrogen responses to humans.

Genes · Mar 17, 2026Peer-reviewedEvolutionary Biology

Divergent mechanics of inner ear morphogenesis are coupled to developmental tempo over vertebrate evolution

Shunya Kuroda, Shuhei A. Horiguchi, Soichiro Kato, Oki Hayasaka, Hiroyasu Kamei, Wataru Takagi, Shinnosuke Higuchi, Tatsuya Hirasawa, Koji Fujimura, Kiyoshi Hiraoka, Nanoka Suzuki, Makoto Suzuki, Hajime Ogino, Anna Yasunaga, Hiroshi Kiyonari, , Okuda Satoru

The paper examines inner ear morphogenesis across 12 vertebrate species, finding that divergent mechanical processes in tissue expansion are coordinated with developmental tempo to maintain conserved morphology.

bioRxiv · Feb 28, 2026 · PreprintEvolutionary Biology

Sharks and rays have the oldest vertebrate sex chromosome with unique sex determination mechanisms

Taiki Niwa, Yoshinobu Uno, Yuta Ohishi, Mitsutaka Kadota, Naotaka Aburatani, Itsuki Kiyatake, Daiki Katooka, Michikazu Yorozu, Nobutaka Tsuzuki, Atsushi Toyoda, Wataru Takagi, Masaru Nakamura, Shigehiro Kuraku

This study identifies the oldest vertebrate sex chromosomes in sharks and rays, revealing a unique dosage-dependent sex determination mechanism distinct from other vertebrates.

Proceedings of the National Academy of Sciences · Jul 22, 2025Peer-reviewedEvolutionary Biology

Low microbial abundance and community diversity within the egg capsule of the oviparous cloudy catshark (Scyliorhinus torazame) during oviposition

Wataru Takagi, Ayami Masuda, Koya Shimoyama, Kotaro Tokunaga, Susumu Hyodo, Yuki Sato‐Takabe

This study investigates the microbial environment inside the egg capsules of cloudy catsharks during oviposition, finding low bacterial density and unique microbial composition that may protect embryos from infection.

Environmental Microbiology Reports · Oct 1, 2024Peer-reviewedMicrobiology

Gluconeogenesis in the YSL-like tissue of cloudy catshark (Scyliorhinus torazame).

Marino Shimizu, Wataru Takagi, Yuki Sakai, Isana Kayanuma, Fumiya Furukawa

This study identifies gluconeogenic activity in the YSL-like tissue of cloudy catshark embryos, suggesting conserved yolk metabolism mechanisms between teleosts and elasmobranchs.

Physiological Reports · May 29, 2024Peer-reviewedPhysiology