Structural architecture of a dimeric paramyxovirus polymerase complex
Jin Zhong Xie, Mohamed Ouizougun-Oubari, Li Wang, Guanglei Zhai, Daitze Wu, Zhaohu Lin, Manfu Wang, Barbara I. Ludeke, Xiaodong Yan, Tobias Nilsson, Lu Gao, Xinyi Huang, Rachel Fearns, Shuai Chen
This study determines the cryo-EM structure of the hPIV3 L-P polymerase complex, revealing structural features and interactions that may explain its dimerization and function in transcription and replication.
Nature Communications · Apr 11, 2024Peer-reviewedMolecular Biology