Author

Mohamed Ouizougun-Oubari

Boston UniversityORCID 0000-0002-2406-0118Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metagenomics· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Andreas MeyerhansiD· 1 shared Barbara I. LudekeiD· 1 shared Carine TisnéiD· 1 shared Cristina Lorca-OróiD· 1 shared Daitze Wu· 1 shared Gilles MirambeauiD· 1 shared Guanglei Zhai· 1 shared Jean‐Christophe PaillartiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Andreas MeyerhansORCID

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2 papers

Recent·Most cited

Structural architecture of a dimeric paramyxovirus polymerase complex

Jin Zhong Xie, Mohamed Ouizougun-Oubari, Li Wang, Guanglei Zhai, Daitze Wu, Zhaohu Lin, Manfu Wang, Barbara I. Ludeke, Xiaodong Yan, Tobias Nilsson, Lu Gao, Xinyi Huang, Rachel Fearns, Shuai Chen

This study determines the cryo-EM structure of the hPIV3 L-P polymerase complex, revealing structural features and interactions that may explain its dimerization and function in transcription and replication.

Nature Communications · Apr 11, 2024Peer-reviewedMolecular Biology

The HIV-1 ribonucleoprotein dynamically regulates its condensate behavior and drives acceleration of protease activity through membraneless granular phase separation

Sébastien Lyonnais, S. Kashif Sadiq, Cristina Lorca-Oró, Laure Dufau, Sara Nieto-Márquez, Tuixent Escribà, Natalia Gabrielli, Xiao Tan, Mohamed Ouizougun-Oubari, Josephine Okoronkwo, Michèle Reboud‐Ravaux, José María Gatell, Roland Marquet, Jean‐Christophe Paillart, Andreas Meyerhans, , Gilles Mirambeau

The paper investigates how HIV-1's RNP granules regulate protease activity through phase separation, revealing key RNA-binding motifs and their role in viral maturation.

bioRxiv · Oct 26, 2021 · PreprintMolecular Biology