Disulfide Crosslinking Induces Rapid Degradation of Arc/Arg3.1 via Hsp70-Mediated Ubiquitin Ligase Pathway
Dami So, In-Kang Song, Yeon Jung Kim, Y.P. Lee, Yeon Seung Park, Hee‐Jung Kim, Kong-Joo Lee, Eun Joo Song
This study identifies a novel degradation pathway for Arc/Arg3.1, showing that disulfide crosslinking promotes rapid degradation via Hsp70-mediated ubiquitination and affects heat shock response.
The FASEB Journal · Mar 19, 2026Peer-reviewedBiochemistry