A Microphysiological Model of Progressive Human Hepatic Insulin Resistance
Dominick J. Hellen, Jessica L. Ungerleider, Erin N. Tevonian, Pierre Sphabmixay, Priyatanu Roy, Nikolaos Meimetis, Federico Presutti, Ashleigh M. Williams, Ryan Ogi, Caroline A. Lewis, Jacob Fuglsbjerg Jeppesen, Sixian You, Damien Demozay, Linda Gay Griffith
This study uses a human liver microphysiological system to investigate how insulin, glucose, and free fatty acids contribute to hepatic insulin resistance and its reversibility.
Communications Biology · Jan 14, 2026Peer-reviewedBioengineering