Allosteric Gating Mechanism Regulates Odorant Selectivity and Antagonism in Odorant Receptors
Ning Ma, Mona A. Marie, Dan Takase, Claudia Llinás del Torrent, Jeremy Aguilar, Aashish Manglik, Hiroaki Matsunami, Nagarajan Vaidehi
This study investigates how odorant receptors regulate selectivity and antagonism through allosteric gating mechanisms using simulations and experiments.
bioRxiv · Jul 10, 2026 · PreprintBiophysics