Mona A. Marie

This study investigates how odorant receptors regulate selectivity and antagonism through allosteric gating mechanisms using simulations and experiments.

The paper shows that rapid odorant metabolism in the olfactory mucosa generates secondary odorants that reshape odor representations by introducing timing-based distinctions between inhaled and internally-generated odorants.

The paper identifies a diverse and variable odorant receptor repertoire in birds, including the kiwi, and reveals gene conversion as a mechanism for generating functional diversity in avian olfaction.

This study shows that the GPR4 antagonist NE-52-QQ57 improves survival, reduces inflammation, and lowers viral load in SARS-CoV-2-infected mice.