Spatially distinct cellular and molecular landscapes define prognosis in triple negative breast cancer
Kavitha Mukund, Darya Veraksa, David Eugene Frankhouser, Lixin Yang, Jerneja Tomšič, Raju K. Pillai, Srijan Atti, Zahra Mesrizadeh, Daniel D. Schmolze, Jovanny Zabaleta, Xiao‐Cheng Wu, Mary-Anne LeBlanc, Lucio Miele, Augusto C. Ochoa, Victoria L. Seewaldt, Shankar Subramaniam
This study uses spatial transcriptomics to identify molecular and cellular differences between good and poor prognosis triple-negative breast cancer subtypes, revealing distinct gene signatures that could inform therapy.
Cell Reports · Dec 31, 2025Peer-reviewedCancer Biology