Author

Daniel O’Brien

University of Leeds

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Holly McIntyre· 1 shared Laura JonesiD· 1 shared Natalie R. CoheniD· 1 shared Patricija van Oosten‐HawleiD· 1 shared Robert H. DoweniD· 1 shared Valeria Uvarova· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperGenetics

Holly McIntyre

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1 paper

Recent·Most cited

Stress-dependent activation of PQM-1 orchestrates a second-wave proteostasis response for organismal survival

Laura Jones, Valeria Uvarova, Daniel O’Brien, Holly McIntyre, Natalie R. Cohen, Robert H. Dowen, Patricija van Oosten‐Hawle

This study identifies PQM-1 as a stress-responsive transcription factor that promotes proteostasis and organismal survival through a secondary wave stress response mechanism.

bioRxiv · Mar 11, 2025 · PreprintGenetics