Cholesterol availability drives the assembly of mitochondria-associated ER membranes
Mónica Uceda, Khushbu Kabra, Andrea C Ferre, Laura Serrano‐cuñarro, Nuria Gómez-López, Marta Pera, Delfina Larrea, Rishi R. Agrawal, Kirstin A. Tamucci, Cristina Anton-Barros, Daniel T Yun, KEVIN R. VELASCO, Eric A. Schon, Jorge Montesinos, Estela Área-Gómez
This study shows that cholesterol availability through HDLs and SR-B1 drives MAM formation, which regulates ER-mitochondria communication and cholesterol metabolism.
bioRxiv · Oct 30, 2026 · PreprintCell Biology