BCL-3 enhances β-catenin signalling in colorectal tumour cells promoting a cancer stem cell phenotype
Danny N Legge, Alex P Shephard, Tracey J Collard, Alexander Greenhough, Adam C Chambers, Richard W Clarkson, Christos Paraskeva, Ann C Williams
This study shows BCL-3 enhances β-catenin signaling in colorectal cancer cells, promoting a cancer stem cell phenotype by increasing stem cell gene expression and tumour sphere formation.
bioRxiv · Aug 18, 2017 · PreprintCancer Biology