Dose-dependent role of Gfi1 in murine hematopoietic stem cell self-renewal and differentiation
Judith Schütte, Aniththa Thivakaran, Yahya Saleh Al-Matary, Pradeep Kumar Patnana, Daria Frank, Daniel Robert Engel, Ulrich Dührsen, Cyrus Khandanpour
This study investigates the dose-dependent role of Gfi1 in murine hematopoietic stem cell self-renewal and differentiation, finding that reduced Gfi1 levels impair myeloid and lymphoid differentiation.
bioRxiv · May 7, 2019 · PreprintMolecular Biology