Inhibition of Mitochondrial Respiration Fragments ER Architecture and Remodels Organelle Contact Sites, as Revealed by FIB-SEM
Andrea Dlasková, Bazila Bazila, Pavel Křepelka, Rhea Christine Victor, Darsh Jaresh Jhala, Petr Ježek
This study uses FIB-SEM to show that mitochondrial dysfunction causes ER fragmentation and remodeling of contact sites in pancreatic β-cells.
bioRxiv · May 25, 2026 · PreprintCell Biology